Biopharmaceutical & Pharmacokinetics Lab

Laboratories of Pharmaceutics discipline provide a range of high-quality research equipment. The facilities are supervised and maintained by well-trained academic and support staff to facilitate interdisciplinary research in the faculty and collaborative research with other faculties across UiTM. We also promote work with other institutions and commercial companies, both nationally and internationally.

Main research activities
:

  • Development of pharmaceutical dosage form
  • Pharmacokinetic study
  • Physical pharmacy study
  • Pharmaceutical nanotechnology study
  • Development of cosmetic product
  • Development of herbal formulation

Name

Brand/Model

Details

Autoclave 58 L

Fedegari/FVG1

To disinfect anything that needs to be free of microorganisms. It can decontaminate solids, liquids, hollow items and instruments of varying shapes.

Automatic Topical and Transdermal Diffusion Cell System

Hanson/Microette Plus

For transdermal drug delivery or skin permeation test by using synthetic membrane or rat skin with automated sample collector

Bench Top Microcentrifuge

ALC/4214

For microcentrifugation with max speed 14000rpm, capacity rotor 20-place 1.5/2.0 ml

Buchi Rotary Evaporator Rotavapor

Buchi/ R-213 basic

This  equipment is design for the efficient and gentle removal of solvent from samples by evaporation.

Refrigerated Centrifuge

Centurion/ K 241 R

Use for sedimentation of mixtures or to separate two immiscible liquids, rotor type BRK5510 (max 4000rpm)

CO2 Incubator

Nuaire/ NU5500E

To maintain an optimal environment for cell growth, by providing carbon dioxide control in a humidified atmosphere with constant temperature

Completed Dry Block 27 holes  & reacti- vap evaporators

Pierce/ 18940

For performing heating and evaporating (by connecting to purified Nitrogen gas) that is required for sample preparation before analysis by GC, HPLC and other applications.

Dispersion Stability Analyzer

L.U.M/ LumiFuge 112

For an easy and fast determination of stability and shelf-life of dispersion

Dissolution Tester

Varian Venke/  VK7000

Dissolution tester with automated sample collector.  Designed for testing of a variety of pharmaceutical compounds, including tablets, capsules, transdermal patches and membranes.

Fast Scan DSC

Perkin Elmer/ Diamond DSC

To measures the amount of energy (heat) absorbed or released by a sample as it is heated, cooled or held at constant temperature. DSC also performs precise temperature measurements.

Fixed Angle Medical Centrifuge

Heraeus/ Labofuge 200

Use for sedimentation of mixtures or to separate two immiscible liquids, can use 5,7,10, and 15ml tube with a 12-place fixed angle rotor, max speed 5300rpm, min speed 1600rpm.

Freeze Dryer

Labconco/ 77530-30

To remove water/moisture from some material such as from solution to powder form (e.g in food industry -make it easier to transport) or in pharmaceutical to increase shelf life of the product, or make them more stable, etc. [condenser reach till -45°C]

Freeze Dryer

Scanvac /  (Coolsafe 110)

To remove water from some material such as from solution to powder form (e.g in food industry -make it easier to transport) or in pharmaceutical to increase shelf life of the product, or make them more stable, etc. [condenser reach till -110°C]

High Intensity Ultrasonic Liquid Processors

SONICS Vibra-cell/  VCX 499

For sample preparation, cell lysing, disaggregation, homogenization, particle size reduction, soil testing, acceleration of chemical reactions, defoaming, and atomization, (e.g. to make the nanoparticle uniformly disperse)

High Pressure Homogenizer

APV / 1000

High-pressure homogenizers are most commonly used for creating emulsions and for cell lysis when relatively large volumes are being processed.

Homogenizer

PRO/ PRO 400 DEL

The PRO400DEL is similar to the PRO400D but has a 41" stand (11 more inches) for homogenizing in taller vessels. It is a reliable, versatile, and durable benchtop homogenizer with a whole lot of power.

Humidity Chamber

Jeiotech/ TH-PE-100

For precision temperature and humidity control

Humidity Chamber

MMM/ CLIMACELL 111

For simulation of various climatic conditions such as testing stability of samples, working condition 0-99.9°C (without humidity) while 0-90°C (with humidity), humidity range 10-90% RH

Incubator

Genlab/ LCI/27V/DIG

The GENLAB Large Capacity Multipurpose Incubators offer a unique range of highly efficient, reliable and accurate units. Temperature range: ambient + 8 to 100ºC

Mastersaizer Particle Size Analyser

Malvern Instrument/ Mastersizer 2000 entry

With accessory Hydro SM - Small volume entry level wet dispersion unit.

The Hydro SM is a cost effective wet sample dispersion unit designed for measuring samples in non-aqueous dispersants where solvent usage needs to be minimized.

Microcentrifuge 5424

Eppendorf/ 5424-000-010

Eppendorf 5424 Microcentrifuge features a 24-place capacity and speed up to 21,130 × g. Patented compressor technology reduces vibrations and protects your samples.

Nano Mill

Netzsch/ Mini Cer

Highly efficient centrifugal separation system enables the use of smallest grinding media from a diameter of 30 – 300 µm in reliable continuous operation. It is specially designed for wet grinding and dispersing processes especially "gentle dispersing" in the nanometer range.

Oven 111L

MMM/ Venticel 111 Comfort

Heating and drying oven with a patented thermospiral ventilation system which ensures faster, more even heating is achieved in the whole chamber

Portable Water Bath 3L

FALC/ BO-D16

Water bath with adjusted temperature range from 5-300°C

Refrigerated Microcentrifuge

Centurion/ K 2015 R

For microcentrifugation with max speed 15000rpm, controlled temperature -9 to 40°C (rotor type 24x2ml)

Rheometer

Anton Paar / Physica MCR301

For characterization of a material and determination of rheological properties, various rheology application test using Cone-and-plate/parallel-plate thermal chambers with Peltier temperature control (-40 to +200 °C), Concentric cylinder thermal chambers (-20 to +200 °C). Five types measuring  geometries available CP25-1, PP25, CP50-1, PP50 and CC17.

Silverson  L4RT  Lab  Mixer  with  Digital Technometer

Silverson/  L4R

Heavy duty mixer for mixing, emulsifying, homogenizing, disintegrating and dissolving, capacity up to 12liter, max speed 8000rpm (6000rpm under full load)

Sunscreen Protection Factor SPF Analyzer  System

Optometrics/ (SPF-290s)

In-vitro evaluation of the sunscreen protection factors of various formulations and materials [determination of SPF value]

Syringe Pump Terufusion

Terumo/ TE-331NW2S

The syringe flow can be controlled, flow rate range 1 – 1200 mL/h, delivery setting range 0.1 – 999.9 mL (in 0.1 mL steps)

Texture Analyzer

Stable Micro Systems / TA.XTplus

For texture analysis, measuring physical product characteristic such as adhesiveness, gel strength, tensile strength, raft strength, lipstick break strength, consistency of cream, spreadability, etc.

Transdermal Franz Diffusion Cell System

Permegear inc/USA/

(V6A-02)

For transdermal drug delivery or skin permeation test by using synthetic membrane or rat skin with manually sample collector (6 slots available per run with receptor volume 7.5ml).

Ultra Low Freezer -86C

GFL/ 6485

To freeze/store sample in temperature -80°C (±2°C)

Ultra Performance Liquid Chromatography (UPLC)

Waters/USA

To separate components in a mixture, to identify and quantify each component (using FLR or PDA detector).

Ultra Turrax Homogenizer

IKA LABTECHNIK ULTRA/ T 25 B

Used for homogenizing, emulsifying or suspending, max speed 24000rpm, max volume 2L  (with digital speed display)

Ultracentrifuge

Beckman Coulter/ Max-TL

For separation a mixture or particles from a solution with exceptional high speed max 120000rpm and temperature range 0 to 40°C. Need to use centrifuge tube 4.7ml (8 slots/run).

Ultrasonic Bath 10L

Liarre/  Starsonic 90

Frequency 28-34kHz, mechanical timer (0-30 minutes), no temperature setting, equipped with stainless steel basket and cover.

Universal Table Top Centrifuge

Heraeus/ Megafuge 1.0

Use for sedimentation of mixtures or to separate two immiscible liquids, with swing out rotor 4x400ml, [Max. RCF: 6,240 x g]

Vacuum Laboratory Reactor

IKA/ LR2.ST

Mini plant reactor system equipped with a 2 liter reactor vessel, heater, stirrer (speed range 8-290rpm), and temperature sensor. Use for mixing, dispersion and homogenization processes such as manufacturing cream, emulsion, min volume(stirring) 500ml,min volume (dispersing) 800ml, max volume 2000ml

Water Bath with Shaker

Julabo/ SW22

To shake samples with controlled temperature, range +20 °C to +99 °C and adjustable shaking frequency 20-200rpm.

Zetasizer 1600 Zeta Potential and Size Analyzer

Malvern Instrument/ (Nano ZS/UK)

To measure zeta potential and also particle size (0.3nm – 10.0 microns).





 

Reservation Application Form

EQUIPMENTS CHARGE RATE (RM)
UNIT CHARGE UiTM PUBLIC INSTITUTE PRIVATE INSTITUTE & INDUSTRIAL
Autoclave 58L per run 25 50 75
Automatic Topical and Transdermal Diffusion Cell System per sample 50 100 150
Microcentrifuge per run 15 30 45
Rotary Evaporator Rotavapor per run 15 30 45
Refrigerated Centrifuge per run 20 45 70
CO2 Incubator per sample/ per day 25 50 75
Completed Dry Block 27 holes & Reacti-Vap Evaporators per sample 10 20 30
Dispersion Stability Analyzer per sample 40 (< 3 Months Stability)
80 (6 Months stability)
150 (1 Year Stability)
200 (2 Years Stability)
60 (< 3 Months Stability)
100 (6 Months Stability)
180 (1 Year Stability)
250 (2 Years Stability)
80 (< 3 Months Stability)
150 (6 Months Stability)
230 (1 Year Stability)
300 (2 Years Stability)
Dissolution Tester** per run 35 80 100
Fast Scan DSC** per sample 50 100 150
add on pan 10 per pan 10 per pan 10 per pan
Fixed Angle Medical Centrifuge per run 15 30 45
Freeze Dryer Labconco per day 50 100 160
Freeze Dryer Scanvac  per day 60 120 150
High Intensity Ultrasonic Liquid Processors

per sample

15 30 45
High Pressure Homogeniser per sample (min 500ml, max 1L) 30 60 90
Homogenizer per sample 30 50 100
Humidity Chamber per sample/per day 10 20 30
Incubator per sample/per day 10 20 30
Mastersizer Particle Size Analyser** per sample 40 90

130

Microcentrifuge per run 15 30 45
Nano Mill per sample 15 30 45
Oven 111L per sample/per day 10 20 30
Portable Water bath 3L per day 15 25 35
Refrigerated Microcentrifuge per run 20 45 70
Rheometer** per sample/per test 50 100 150
Silverson L4RT Lab Mixer with Digital Technometer per sample 30 50 100
Sunscreen Protection Factor SPF Analyzer System per sample 30 60 90
Syringe Pump Terufusion per day 10 20 30
Texture Analyzer per sample per one application 40 80 120
Transdermal Franz Diffusion Cell System per sample 15 30 45

Ultra Low Freezer -86C

per day

15 30 45
Ultra Performance Liquid Chromatography (UPLC )** per sample 50 100 150
Ultra Turrax Homogenizer per sample 10 15 20
Ultracentrifuge, Beckman Coulter** Price excluded sample tube (Sample tube RM35 / tube) aqueous form per run 200 260 320
Ultrasonic Bath 10L per day 10 20 30
Universal Centrifuge, Megafuge 1.0 per run 15 30 45
Vacuum Laboratory Reactor per one mixing 25 50 75
Water Bath with Shaker per run 15 30 45
Zetasizer per sample 40 (zeta potential only)
60 (size & zeta potential)
90 (zeta potential only) 120 (size & zeta potential) 130 (zeta potential only) 160 (size & zeta potential)
Skin Topography per day 30 60/panelist 80/panelist
Ice Flake Maker per bucket 0 3 3
Semi Micro Balance per sample 50 60 80
Glass Tube Homogenizer per sample 3 5 8
Tube Roller per day 25 50 50
Orbital Shaker per day 25 50 50
pH Meter per sample 15 25

30

Conductivity Meter per sample 15 25 30
**1 Service Does Not Include Chemicals / Disposal Materials

Faculty of Pharmacy,
UiTM Selangor, Puncak Alam Campus
42300 Bandar Puncak Alam
Selangor, MALAYSIA
Fax No: +603-32584602

Dr. Tommy Julianto Bustami Effendi
Head of Biopharmaceutical & Pharmacokinetic Lab
03-32584621
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Siti Fariha Bakri
Science Officer
03-32584702
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Noor Meliza Jamil
SeniorAssistant Science Officer
03-32584682
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Contact Us

Faculty of Pharmacy
Level 11, FF1 Building
UiTM Selangor, Puncak Alam Campus
42300 Bandar Puncak Alam

Selangor. MALAYSIA

pharmacyuitm@uitm.edu.my
farmasiuitm@gmail.com

Tel : +603 - 32584645
Fax : +603 - 32584602